Opti-Build™ Study

Creatine Amino Chelate compared to Creatine Monohydrate

Opti-Build ™ is composed of the most powerful strength increasing and muscle building ingredients ever proven to help increase anabolism, specifically, a patented creatine amino acid chelate blend, patented, stabilized glutamine (Magnesium Glycl Glutamine), and the branch chain amino acids Leucine, Isoleucine and Valine.

Numerous studies have shown that creatine improves athletic performance and delays muscle fatigue. The mechanism behind this phenomenon involves creatine’s ability to increase the production of phosphocreatine in the muscle tissue, a needed component for the formation of adenosine triphosphate (ATP). ATP is the muscle’s main source of energy and is needed by the body for numerous other functions. Research shows that total creatine and muscle phosphocreatine stores can be increased significantly with Creatine Monohydrate supplementation. Studies indicate that it only takes one hour for a single dose of five grams of creatine to increase creatine plasma levels to a peak, with a return to pre-supplement levels within five hours . These measures indicate that the serum half-life of creatine is approximately two hours, which would give the five grams of creatine supplementation a serum life span of fourteen hours. Unfortunately, Creatine Monohydrate has also been shown to increase creatinine levels in the body. Excess creatinine has been shown to increase kidney damage and cause other renal problems.. Studies show that Creatine Monohydrate in supplemental form may become unstable and has the ability to turn into creatinine because of this instability. In response to this new understanding, Creatine Amino Acid Chelate has been created. Creatine Amino Acid Chelate is a completely stable molecule that, on its own, is much more effective than Creatine Monohydrate. It also helps to enhance the absorption and bioavailability of Creatine Monohydrate. By combining the two forms of creatine, Albion Laboratories found that it intensified their test subjects’ ability to generate and regenerate the ATP needed to out-perform, by a wide margin, the performance of the test subjects taking Creatine Monohydrate alone. The additional advantage to this new molecule is that magnesium is one of the binding agents, and – because of its chelation to creatine and glycine – it is much more effective at increasing protein synthesis. Magnesium is necessary for the metabolism and production of ATP. ATP is formed via the Myokinase and the Creatine Phosphokinase reactions, which require magnesium to catalyze their energy producing reactions. In summary, the presence of magnesium is necessary for creatine to synthesize and regenerate ATP. Albion’s Creatine Amino Acid Chelate not only surpasses all other creatine compounds for absorption, it is also the safest. Toxicology studies show that ingestion of up to 2,000 mg of Albion’s Creatine Amino Acid Chelate per kg body weight (or 164 gm for a 180 lb. man) produced no side effects in animals.

Glutamine is an amino acid that plays an important role in promoting muscle protein synthesis, counteracting muscle catabolism, and supporting the immune system. Glutamine also neutralizes acidosis in the intestinal tract, enhances intestinal absorption of nutrients, and can act as an energy source. Skeletal muscle is the primary storage site for glutamine, but glutamine is also found in small amounts in various other locations in the body. A healthy diet provides 5-8 grams per day. Food sources of glutamine include high protein foods such as meat, poultry, fish, beans, and dairy products. The body can also make glutamine. Studies show that the changes in intestinal glutamine metabolism are intimately tied to the needs of the liver for substrates, and in particular amino acids, to meet the increased demands for enhanced glucose utilization during exercise. Other research showed that glutamine stimulates the secretion of growth hormone. Growth hormone levels increased by 430% and remained above baseline levels for more than an hour and a half after ingestion. This study showed that even small levels of glutamine optimize the stimulation of hGH production in the pituitary gland and cause its prolonged distribution throughout the body. However, strenuous exercise, infection, and trauma can severely deplete the body’s glutamine stores and can cause temporary glutamine deficiency. In fact, glutamine is critical to the body’s ability to create new muscle tissue. It has been called the non-essential/essential amino acid because of its increasing deficiency in humans. A deficiency in glutamine contributes to muscle wasting, reduced immune response, and decreased multi-organ function. The total pool of muscle free intracellular amino acids consists of 60% glutamine, and 19% of a glutamine molecule is made up of nitrogen, making it the primary conductor of nitrogen to the muscles. During catabolic stress, due to exercise or other factors, a marked reduction of over 50% of this glutamine pool occurs.

Although it is known that glutamine supports the optimal functioning of vital organs and systems, providing bioavailable glutamine in a supplemental form has always been a problem. The free-form glutamines and L-glutamines available in most health food stores are not stable and decompose readily in the digestive tract and are, therefore, unable to sufficiently provide the benefits listed above except in large dosages and with some possible toxic build up. The patented glutamine molecule in Opti-Build™ is the only stabilized form available today. Studies show that the Stabilized Magnesium Glycl Glutamine molecule, , remains stable in solution and is readily assimilated into the mucosal cell. It's ability alone to increase recovery of the muscle tissue is a phenomenal step forward in being able to build the lean muscle tissue needed to compete with and even surpass that of anabolic steroids safely and effectively.

The other key factor that is critical for muscle tissue synthesis is Branched Chain Amino Acids (BCAA's). The branched chain amino acids consist of Leucine, Isoleucine, and Valine. These three amino acids make up one third of the muscle intake after exercise. During intense exercise and in conditions of a relative lack of energy, the metabolism of the BCAA's is accelerated in muscle. It has been proven that the administration of BCAA's during short-term and long-term exercise resulted in significantly greater muscle NH3 and glutamine production, as well as lower lactate production, than is observed during exercise without BCAA supplementation. The amount of each amino acid is critical for protein synthesis. Studies on muscle catabolism and one study in particular, conducted through Arizona State University, have determined the exact amounts needed to support anabolism.

The combination of these ingredients promises to promote optimum muscle growth, improve athletic performance, and delay muscle fatigue. There are no fillers used in this product, which is an extreme benefit to the serious athlete wanting to avoid taking in additional, unneeded calories from sugar fillers found in most other formulations.

References

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NOTE: This product is intended to be distributed to serious athletes throughout professional sports and to a few select individuals needing to build muscle strength and size without using harmful drugs.